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UID:20260205T023944EST-2618gSZUjs@132.216.98.100
DTSTAMP:20260205T073944Z
DESCRIPTION:Speaker: Professor Mathieu Blanchette\nTitle: Vertebrate Compar
 ative and Regulatory Genomics\nAbstract: This talk will bring together my 
 two\npassions\, genome evolution and gene regulation\, and will discuss\nw
 hat the former can teach us about the latter. We have recently\nshown that
  the genome of an ancestral mammal living about 70\nMillion years ago can 
 be computationally reconstructed to a\nsurprising degree of accuracy from 
 the genomes of extant species.\nIn the first part of this talk\, I will in
 troduce some of the\ncomputational challenges related to the accurate reco
 nstruction of\nan ancestral genome. I will then describe how this new geno
 me\,\nstrategically positioned at the center of the mammalian radiation\,
 \nallows a detailed study of the evolution of transcriptional\nregulatory 
 regions. Finally\, I will describe how whole-genome\nanalyses based in par
 t on comparative genomics reveal new and\nunexpected traits of mammalian r
 egulatory regions\, both those\nlocated in non-coding regions and those hi
 ding within\nprotein-coding DNA.\n \n
DTSTART:20090212T230000Z
DTEND:20090212T230000Z
LOCATION:CA\, 3649 Promenade Sir-William-Osler\, 3649 Promenade Sir-William
 -Osler\, Bellini Building\, Life Scinces Complex\, Montreal
SUMMARY:MonBUG Seminar
URL:/channels/event/monbug-seminar-104333
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