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Ghrelin promotes conditioning to food-related odours

The holiday season is a hard one for anyone watching their weight. The sights and smells of food are hard to resist. One factor in this hunger response is a hormone found in the stomach that makes us more vulnerable to tasty food smells, encouraging overeating and obesity. New research on the hormone ghrelin was published on Dec. 4, 2018, led by Dr. Alain Dagher’s lab at the Montreal Neurological Institute and Hospital of Թ.

Classified as: alain dagher, fMRI, obesity, Canadian Institutes of Health Research, CIHR, ghrelin, appetite
Published on: 12 Dec 2018

How does cancer spread? While studying human brain tumour cells, a team of scientists at the Research Institute of the Թ Health Centre (RI-MUHC) found some answers to this crucial, yet so far unanswered question. They looked at a gene called EGFRvIII, which is present in patients with glioblastoma – a highly aggressive form of brain cancer that spreads quickly and that is difficult to treat.

Classified as: Cancer, oncogenes, Research Institute of the Թ Health Centre, EGFRvIII, exosomes
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Published on: 10 Dec 2018

There are only 25 people in the whole of Quebec at the moment who have a rare recessive genetic disease called chronic atrial and intestinal dysrhythmia (CAID). It is a serious disease that affects both heart rate and intestinal movements. A Թ-led research team has been able to trace the gene mutations underlying the disease back to two European founding families who arrived in the province in the 17th century.

Classified as: genetics, Genomic research, mcgill faculty of medicine research
Published on: 7 Dec 2018

A team from the Research Institute of the Թ Health Centre (RI-MUHC) led by Dr. Donald Vinh, the RI’s so-called “Dr. House” because of his research into rare diseases, has discovered a new human disease and the gene responsible for it, paving the way for the proper diagnosis of patients globally and the development of new therapies. Their findings are published in the Journal of Experimental Medicine.

Classified as: Research Institute of the Թ Health Centre (RI-MUHC)
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Published on: 6 Dec 2018

Mice represent well over half of the non-human subjects of biomedical research, and the vast majority of those mice are inbred. Formed by generation after generation of mating between brothers and sisters, inbred mice are genetically identical to each other, like twins or clones. Inbreeding is well known to reduce health and vigor across species; this biological fact is the reason that incest is a universal taboo.

Classified as: Biomedical research, Nature Methods, Թ, Jeffrey Mogil, inbred mice, outbred mice
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Published on: 4 Dec 2018

The Canadian Institute for Advanced Research (CIFAR) today announced the inaugural cohort of 29 Canada CIFAR AI (CCAI) Chairs, including six from Թ. These top academic researchers—including Doina Precup and Joëlle  Pineau—are named as part of the $125 million Pan-Canadian AI Strategy, and will help maintain Canada’s leadership in artificial intelligence research. The CCAI Chair Program represents an investment of $30 million at nine universities across the country.  

Classified as: CIFAR, Azrieli Canadian Institute for Advanced Research (CIFAR), Artificial intelligence
Published on: 3 Dec 2018

HIV self-testing strategies have been recommended by the World Health Organization (WHO) since 2016, as they empower people to find out HIV their status at their convenience. However, home-based testing kits have yet to be approved for sale in Canada.

Classified as: HIV, Research Institute of the Թ Health Centre (RI-MUHC), nitika pant pai, Réjean Thomas, HIVSmart!
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Published on: 30 Nov 2018

What makes people take risks? Not stunt women or formula 1 drivers. Just ordinary people like you and me. Research published this week in PLOS ONE suggests that unexpected improvements in everyday life (sunshine after many days of rain or a win by a local sports team) are correlated with a change in a city’s mood and an increased likelihood that it’s citizens will do risky things like gamble.

Social media and city mood

Cities seem to have moods that fluctuate from day to day. Now, thanks to social media, these city moods are also measurable.

Classified as: science, Research, psychology, gambling, Faculty of Science
Published on: 28 Nov 2018

Source: Max Bell School of Public Policy

Public Policy Forum President & CEO Edward Greenspon and recently appointed Max Bell School of Public Policy professor Taylor Owen announced the launch of a multi-year project to analyze and respond to the increasing amounts of disinformation and hate in the digital public sphere.

Classified as: max bell school, Digital Democracy Project (DDP)
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Published on: 27 Nov 2018

Reducing stigma may address cognitive impairment in this population

A new study has drawn a direct link between the amount of stigma men with HIV report experiencing and their scores on cognitive tests, measuring abilities such as memory and attention.

Classified as: AIDS, HIV, human immunodeficiency virus, Cognitive neuroscience, Lesley Fellows, stigma, psychology
Published on: 27 Nov 2018

Concerns raised about efficacy of off-label use of already approved drugs

A new paper published by Թ researchers in JAMA Internal Medicine suggests that some clinical trials may promote the use of ineffective and costly treatments. That’s the opposite of what clinical trials are aimed at, namely preventing ineffective and costly treatments from being taken up by physicians and patients.

Published on: 26 Nov 2018

By Jason Clement

“My father, who inspired me very much, would tell me ‘You must study and make a contribution to science’,” says renowned Թ Professor Nahum Sonenberg reflecting back beyond the beginning of his remarkable career. “My exact career path of course I couldn’t predict, but I knew that I wanted to better understand how the human body works, how to cure disease, and that’s what I’m doing.”

Classified as: Nahum Sonenberg, Prix du Québec
Published on: 22 Nov 2018

The first round of the Թ-Western Collaboration Grant awards were announced today, showcasing the unique research partnership between and Թ’s Healthy Brains for Healthy Lives (HBHL) initiative.

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Published on: 22 Nov 2018

By Fergus Grieve, Communications Strategist, Faculty of Science

Alfonso presented with the Prix Acfas Michel-Jurdant in recognition of his outstanding work on the health of the St. Lawrence Estuary and the world’s oceans Hombeline Dumas
Alfonso Mucci, professor in the Department of Earth and Planetary Sciences, was among nine of Quebec’s leading academics honoured by the Association francophone pour le savoir (Acfas) for their exceptional contribution to research at the Acfas Gala held in Montreal on November 13.

Published on: 20 Nov 2018

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