BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260203T131954EST-4631Rt8Pb0@132.216.98.100 DTSTAMP:20260203T181954Z DESCRIPTION:Eric J. Tchetgen Tchetgen\, PhD\n\nProfessor of Statistics and Data Science | Wharton School |\n University of Pennsylvania\n\nWhere: Virt ual | Zoom\n\nAbstract\n\nA standard assumption for causal inference from observational data is that one has measured a sufficiently rich set of cov ariates to ensure that within covariates strata\, subjects are exchangeabl e across observed treatment values. Skepticism about the exchangeability a ssumption in observational studies is often warranted because it hinges on one's ability to accurately measure covariates capturing all potential so urces of confounding. Realistically\, confounding mechanisms can rarely if ever\, be learned with certainty from measured covariates. One can theref ore only ever hope that covariate measurements are at best proxies of true underlying confounding mechanisms operating in an observational study\, t hus invalidating causal claims made on basis of standard exchangeability c onditions. Causal learning from proxies is a challenging inverse problem w hich has to date remained unresolved. In this paper\, we introduce a forma l potential outcome framework for proximal causal learning\, which while e xplicitly acknowledging covariate measurements as imperfect proxies of con founding mechanisms\, offers an opportunity to learn about causal effects in settings where exchangeability on basis of measured covariates fails. S ufficient conditions for nonparametric identification are given\, leading to the proximal g-formula and corresponding proximal g-computation algorit hm for estimation\, both generalizations of Robins' foundational g-formula and g-computation algorithm\, which account explicitly for bias due to un measured confounding. Both point treatment and time-varying treatment sett ings are considered\, and an application of proximal g-computation of caus al effects is given for illustration.\n\nLearning Objectives\n\n\n Reasonin g about unmeasured confounding using proxies\n Nonparametric identification \n g-computation\n\n\nSpeaker Bio\n\nEric J Tchetgen Tchetgen is The Luddy Family President's Distinguished Professor and Professor of Statistics and Data Science at the Wharton School of the University of Pennsylvania. He also co-directs the Penn Center for Causal Inference\, which supports the development and dissemination of causal inference methods in Health and So cial Sciences. He has published extensively on Causal Inference\, Missing Data and Semiparametric Theory with several impactful applications ranging from HIV research\, Genetic Epidemiology\, Environmental Health and Alzhe imer's Disease and related aging disorders. He is an Amazon scholar workin g with Amazon scientists on a variety of causal inference problems in the Tech industry space. Professor Tchetgen Tchetgen is an 2022 inaugural co-r ecipient of the newly established Rousseeuw Prize for statistics in recogn ition for his work in Causal Inference with applications in Public Health and Medicine.\n\n \n\n \n\n \n\n \n\n \n DTSTART:20230313T200000Z DTEND:20230313T210000Z SUMMARY:An Introduction to Proximal Causal Inference URL:/epi-biostat-occh/channels/event/introduction-prox imal-causal-inference-346771 END:VEVENT END:VCALENDAR