TB Dictionary
Along with Alberto Garcia-Basteiro and many others, Marcel co-piloted the creation聽and editing of the Global TB Dictionary, a consensus TB dictionary to unify the language we speak.
Since its launch in 2024, the TB Dictionary has had 23,000 views by 2,900 total users.
Alberto L Garcia-Basteiro, Joanna Ehrlich, Maryline Bonnet, Marianne Calnan, Stephen M Graham, Sabine Hermans, Adriana Jarrett, Rhoda Lewa, Anna Mandalakas, Leonardo Martinez, Giovanni Battista Migliori, Catherine WM Ong, Larissa Otero, Molebogeng Xheedha Rangaka, Mario CB Raviglione, Barbara Seaworth, Willy Ssengooba, Grant Theron, Anete Trajman, Marcel A Behr.听.听Lancet Global Health, The, 2024-05-01, Volume 12, Issue 5, Pages e737-e739, Copyright 漏 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
BCG strains that are mono-resistant to drugs used for TB
Sarah Danchuk has engineered a panel of recombinant BCG strains that are mono-resistant to drugs used for TB. Strains available by request or also deposited at the BCCM/ITM Mycobacteria collection.
Danchuk S, McIntosh F, Jamieson FB, May K, Behr MA. . Clinical Microbiology and Infection, 2020 Mar; 26(3): 384.e5-384.e8聽
The rBCG strains have been used in聽Sarah N Danchuk, Ori E Solomon, Thomas Andreas Kohl, Viola Dreyer, Ivan Barilar, Christian Utpatel, Stefan Niemann, Dick van Soolingen, Richard Anthony, Jakko van Ingen, Joy S Michael, Marcel A Behr.听.听Thorax. 2024 Jun 14;79(7):670-675. doi: 10.1136/thorax-2023-220202.
Ancestral sequence for the Mycobacterium tuberculosis complex
Luke Harrison has imputed the ancestral sequence for the Mycobacterium tuberculosis聽complex, called MTBC 0.听The sequence can also be accessed via Mycobrowser.
Harrison LB, Kapur V,聽Behr MA.听.听Microb Genom. 2024 Jan;10(1):001165. doi: 10.1099/mgen.0.001165.PMID:聽38175684
Previous work
Graphical user interface for Genomic Sequence Comparison
MycoHit is a JAVA application
This program serves to perform BLAST searches then parses the TBLASTN result files with PERL scripts in order to select the highest score for each protein. Obtained data, including the score, are then stored on a local MYSQL database. It was first published in :
Veyrier F, Pletzer D, Turenne C, Behr MA.. BMC Evol Biol. 2009 Aug 10;9:196. doi: 10.1186/1471-2148-9-196.
Contact
Contact lynn.derycapes [at] mail.mcgill.ca (Lynn Dery Capes) if you wish to receive a zipped copy of the files and instructions for this application.